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What causes virulence in malaria?

by Prof. Thomas E. Wellems (Chief, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892-8132 USA)

Asia/Kolkata
Auditorium (Colaba Campus)

Auditorium

Colaba Campus

Description
Most malaria cases do not result in death. However, virtually all children habiting intense transmission areas suffer multiple and repeated infections in their early years. Before the availability of modern medical care, an estimated 20% of children in highly malarious regions perished due to P.falciparum infections before they reached a reproductive age. This mortality may have put great selective pressure on the human genome with respect to drug resistance, immune evasion,and disease virulence.
Poster